Integrated Prevention Campaigns Featured at AIDS 2012
New Data At AIDS 2012 Conference Shows Impact And Cost Effectiveness Of Integrated Prevention Campaigns To Combat HIV, Malaria And Waterborne Diseases
Washington D.C., 25 July — New evidence presented this week at the International AIDS Society conference demonstrates that integrated prevention campaigns are cost-effective, lifesaving, and reduce diseases’ impact on a population’s productivity. These campaigns, which bundle health interventions targeting multiple diseases, hold significant promise for making headway against disease in a resource-constrained international aid environment.
Studies shared at the conference evaluated an integrated prevention campaign conducted by the Government of Kenya, Vestergaard Frandsen, and partners that reached 47,000 people in seven days in the country’s Western Province. It provided HIV testing and counseling, water filters, insecticide-treated bed nets, condoms and, for HIV-positive individuals, cotrimoxazole prophylaxis and referrals for ongoing care.
The first study, led by researchers from the University of Washington, confirmed that people living with HIV who used the bed nets to fight malaria and household water filters to prevent waterborne diseases showed a delayed progression of HIV. Essentially, they stayed healthier longer, and commencement of antiretroviral treatment (and the associated cost) was delayed. In one trial, the combined interventions resulted in a 27 percent reduction in the likelihood of reaching a CD4 count of less than 350 during the period of study. (A CD4 count of 350 is the threshold for initiating antiretroviral treatment.)
A second University of Washington study took this 27 percent figure and extrapolated it to all of sub-Saharan Africa. Using a computer model, researchers found that providing bed nets and water filters to adults living with HIV-1 (and not yet eligible for antiretroviral therapy) would result in treatment related cost savings of US $402 million, or about 8 percent of the annual PEPFAR HIV care and treatment budget (US $4.9 billion). The intervention would result in 2,070,000 years-of-life saved, with a cost-effectiveness of US $267 per disability-adjusted life year (DALY).
A third study, led by the University of California, modeled the potential cost effectiveness of a scaled up integrated prevention campaign and found that, per 1,000 participants, the projected reduction in cases of diarrhea, malaria and HIV infection avert an estimated 16.3 deaths and save 359 disability-adjusted life years. Accounting for estimated campaign costs, the pilot campaign used in the model saves an estimated $16,015 in healthcare costs for every 1,000 participants.
Finally, a fourth study illustrates that giving HIV-positive mothers water purifiers can reduce deadly diarrhea in their children. The research, conducted by the London School of Hygiene and Tropical Medicine in Zambia, has shown a 53 percent reduction in prevalence of diarrhea in under-twos with HIV-positive mothers who use the filters, and a 54 percent reduction of diarrhea in all household members.
“It’s scientific results like these that together make the case for novel solutions to some of the most pressing problems in aid and public health,” said Mikkel Vestergaard Frandsen, CEO of Vestergaard Frandsen. The company manufactures the LifeStraw water filters and PermaNet bed nets used in the Kenyan integrated prevention campaign.
Mr. Vestergaard Frandsen was also among a group of more than 20 CEOs from the world’s leading companies who signed a pledge this week calling on countries to lift travel restrictions for people living with HIV.
Vestergaard Frandsen is a European company specializing in disease control products and novel ways to distribute them. The company operates under a unique humanitarian entrepreneurship business model, and strong support of the UN Millennium Development Goals is one of its defining characteristics. The aforementioned studies analyzed interventions in which Vestergaard Frandsen’s PermaNet®, LifeStraw® Family, and CarePack® products were distributed. For more information please visit www.carepack.com and www.vestergaard-frandsen.com.